The mysterious smile of the famed portrait 'The Mona Lisa' has confused both art historians and researchers for many years. The nature of the model's enigmatic smile has been explained as the smile of a new, joyous mother, Lisa Gherardini, who had developed Bell's palsy during her recent pregnancy. Bell palsy which is acute in onset, unilateral, and is considered to be idiopathic is the most common cause of peripheral facial nerve paresis and paralysis. We report an idiopathic facial paralysis (Bell's palsy) as Mona Lisa Syndrome in a 24 years old primigravid woman at 34 weeks of gestation.