HAIRAN syndrome is a very rare syndrome which manifests with hyperandrogenism, insulin resistance and acanthosis nigricans. The syndrome usually presents with symptoms during adolescent period of life time. These pattients can easily be misdiagnosed as polycystic ovary syndrome both of which has resembling signs and symptoms. Clinical examination, gynecological evaluation and laboratory investigations are mandatory to differentiate these two syndromes. Metabolic consequences of the syndrome increases the risk of cardiovasculary disease in the future life of these adolescent patients. Counseling about the importance of weight reduction and control of insulin resistance by utilization of medical treatment for menstrual irregularies and hirsutism are key steps during management of this syndrome.

Authors: Erdinc Saridogan, Serkan Kahyaoglu, Yasemin Tasci, Sebnem Ozyer, Omer Hamid Yumusak, Salim Erkaya

Key Words: HAIRAN syndrome, hyperandrogenism, insulin resistance, acanthosis nigricans