Concomitant ovarian tumors are rare neoplasms that usually contain germ cell tumors of origin. Their prognosis worsens when it is associated with more malignant germ cell neoplasm. A 15-year-old virgin girl was consulted to our clinic with the diagnosis of abdominal mass. CA125, LDH and B-HCG levels are elevated. On ultrasonography bilateral pelvic mass was observed. Pathological examination revealed choriocarcinoma and gonadoblastoma in the left ovary and dysgerminoma in the right ovary. According to our investigation this is the first case that these three malignancies concomitantly present in one patient in literature. Coexistence of gonadoblastoma and a choriocarcinoma with the same gonad suggests that gonadoblastomas are genetically unstable and can give rise to other germ cell tumors.

Authors: Emre Ozgu, Burcin Salman Ozgu, Levent Sirvan, Mustafa Besli, Leyla Mollamahmutoglu, Tayfun Gungor

Key Words: Choriocarcinoma, gonadoblastoma, dysgerminoma, concomitant tumors